{"id":1077204,"date":"2026-08-18T00:10:22","date_gmt":"2026-08-17T15:10:22","guid":{"rendered":"https:\/\/thekoreantoday.com\/mapo\/2026\/08\/17\/%e4%bb%8e%e7%97%85%e6%af%92%e7%9a%84rna%e4%bf%9d%e6%8a%a4%e7%ad%96%e7%95%a5%e4%b8%ad%ef%bc%8c%e6%89%be%e5%88%b0%e6%8f%90%e5%8d%87mrna%e7%96%97%e6%b3%95%e6%80%a7%e8%83%bd%e7%9a%84%e9%92%a5%e5%8c%99\/"},"modified":"2026-08-18T00:10:28","modified_gmt":"2026-08-17T15:10:28","slug":"%e4%bb%8e%e7%97%85%e6%af%92%e7%9a%84rna%e4%bf%9d%e6%8a%a4%e7%ad%96%e7%95%a5%e4%b8%ad%ef%bc%8c%e6%89%be%e5%88%b0%e6%8f%90%e5%8d%87mrna%e7%96%97%e6%b3%95%e6%80%a7%e8%83%bd%e7%9a%84%e9%92%a5%e5%8c%99","status":"publish","type":"post","link":"https:\/\/thekoreantoday.com\/mapo\/2026\/08\/18\/%e4%bb%8e%e7%97%85%e6%af%92%e7%9a%84rna%e4%bf%9d%e6%8a%a4%e7%ad%96%e7%95%a5%e4%b8%ad%ef%bc%8c%e6%89%be%e5%88%b0%e6%8f%90%e5%8d%87mrna%e7%96%97%e6%b3%95%e6%80%a7%e8%83%bd%e7%9a%84%e9%92%a5%e5%8c%99\/","title":{"rendered":"\u4ece\u75c5\u6bd2\u7684&#8217;RNA\u4fdd\u62a4\u7b56\u7565&#8217;\u4e2d\uff0c\u627e\u5230\u63d0\u5347mRNA\u7597\u6cd5\u6027\u80fd\u7684\u94a5\u5319"},"content":{"rendered":"<p>&nbsp;<\/p>\n<p>\u75c5\u6bd2\u5728\u6570\u767e\u4e07\u5e74\u8fdb\u5316\u8fc7\u7a0b\u4e2d\u638c\u63e1\u7684&#8217;\u9057\u4f20\u4fe1\u606f\u751f\u5b58\u7b56\u7565&#8217;\u88ab\u5927\u89c4\u6a21\u63ed\u793a\u3002\u8fd9\u662f\u4e00\u79cd\u53ef\u5ef6\u957fRNA\u5bff\u547d\u3001\u663e\u8457\u63d0\u5347\u86cb\u767d\u8d28\u751f\u6210\u7684\u8c03\u63a7\u539f\u7406\uff0c\u6709\u671b\u7528\u4e8e\u63d0\u5347mRNA\u75ab\u82d7\u548c\u6cbb\u7597\u836f\u7269\u7684\u6027\u80fd\u3002<\/p>\n<p>&nbsp;<\/p>\n<table 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\uae30\uc790<\/span><\/p>\n<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<p>&nbsp;<\/p>\n<p>\u97e9\u56fd\u79d1\u5b66\u6280\u672f\u4fe1\u606f\u901a\u4fe1\u90e8(\u526f\u603b\u7406\u517c\u79d1\u5b66\u6280\u672f\u4fe1\u606f\u901a\u4fe1\u90e8\u957f\u5b98\u88f4\u656c\u52cb)\u8868\u793a\uff0c\u57fa\u7840\u79d1\u5b66\u7814\u7a76\u9662(IBS\uff0c\u9662\u957f\u5f20\u9521\u798f)RNA\u7814\u7a76\u56e2\u91d1\u5f6c\u6765\u56e2\u957f(\u9996\u5c14\u5927\u5b66\u8bb2\u5ea7\u6559\u6388)\u7684\u7814\u7a76\u56e2\u961f\uff0c\u5927\u89c4\u6a21\u5206\u6790\u4e86\u611f\u67d3\u810a\u690e\u52a8\u7269\u7684297\u4e2a\u5c5e(genera)\u3001337\u79cd\u75c5\u6bd2\uff0c\u53d1\u6398\u51fa\u591a\u79cd\u53ef\u63d0\u5347RNA\u7a33\u5b9a\u6027\u548c\u86cb\u767d\u8d28\u751f\u6210\u7684\u8c03\u63a7\u8981\u7d20\uff0c\u5e76\u63ed\u793a\u4e86\u5176\u8fd0\u4f5c\u539f\u7406\u3002\u8be5\u7814\u7a76\u6210\u679c\u4e8e\u97e9\u56fd\u65f6\u95f48\u670814\u65e50\u65f6\u520a\u767b\u5728\u4e16\u754c\u6700\u5177\u6743\u5a01\u7684\u5b66\u672f\u671f\u520a\u300a\u7ec6\u80de\u300b(Cell)\u4e0a\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u75c5\u6bd2\u4ee5\u6781\u5c0f\u7684\u57fa\u56e0\u7ec4\u4e3a\u4e86\u9ad8\u6548\u8fd0\u4f5c\u81ea\u8eab\u7684\u9057\u4f20\u4fe1\u606f\uff0c\u8fdb\u5316\u51fa\u7cbe\u5de7\u5229\u7528\u5bbf\u4e3b\u7ec6\u80deRNA\u8c03\u63a7\u7cfb\u7edf\u7684\u80fd\u529b\u3002\u5c24\u5176\u662f\uff0c\u86cb\u767d\u8d28\u751f\u4ea7\u6240\u9700\u7684mRNA\u672b\u7aef&#8217;poly(A)\u5c3e\u5df4&#8217;\u4e00\u65e6\u7f29\u77ed\uff0cmRNA\u4fbf\u5bb9\u6613\u88ab\u964d\u89e3\uff0c\u800c\u75c5\u6bd2\u5219\u53d1\u5c55\u51fa\u5229\u7528\u5bbf\u4e3b\u7ec6\u80deRNA\u8c03\u63a7\u9176\u6765\u4fdd\u62a4\u8fd9\u6761\u5c3e\u5df4\u7684\u7b56\u7565\u3002poly(A)\u5c3e\u5df4\u662f\u7531\u6784\u6210RNA\u7684\u56db\u79cd\u78b1\u57fa\u4e4b\u4e00\u2014\u2014\u817a\u560c\u5464(A)\u8fde\u7eed\u6392\u5217\u800c\u6210\u7684\u7ed3\u6784\uff0c\u6709\u52a9\u4e8emRNA\u7684\u7a33\u5b9a\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u7814\u7a76\u56e2\u961f\u5e0c\u671b\u5c06\u75c5\u6bd2\u7684\u8fd9\u4e00\u7b56\u7565\u7528\u4e8e\u63d0\u5347mRNA\u75ab\u82d7\u548c\u6cbb\u7597\u836f\u7269\u7684\u7a33\u5b9a\u6027\u3002\u6b64\u524d\u57282023\u5e74(Cell)\u548c2025\u5e74(Nature Biotechnology)\u7684\u7814\u7a76\u4e2d\uff0c\u56e2\u961f\u5df2\u53d1\u6398\u51fa\u75c5\u6bd2\u7684RNA\u7a33\u5b9a\u5316\u8981\u7d20\uff0c\u5e76\u5c06\u5176\u5e94\u7528\u4e8e\u6cbb\u7597\u7528mRNA\uff0c\u8bc1\u5b9e\u53ef\u63d0\u5347\u5176\u7a33\u5b9a\u6027\u548c\u86cb\u767d\u8d28\u751f\u4ea7\u3002\u4e0d\u8fc7\uff0c\u4ee5\u5f80\u7814\u7a76\u4ee5\u90e8\u5206\u75c5\u6bd2\u548c\u4e2a\u522b\u8981\u7d20\u4e3a\u4e3b\uff0c\u96be\u4ee5\u7cfb\u7edf\u6027\u5730\u638c\u63e1\u5404\u7c7b\u75c5\u6bd2\u8fdb\u5316\u51fa\u7684\u8c03\u63a7\u7b56\u7565\u3002<\/p>\n<p>&nbsp;<\/p>\n<p>\u5728\u672c\u6b21\u7814\u7a76\u4e2d\uff0c\u7814\u7a76\u56e2\u961f\u5c06\u591a\u8fbe337\u79cd\u75c5\u6bd2\u7684\u57fa\u56e0\u7ec4\u5206\u5272\u5408\u6210\u4e3a\u7ea620\u4e07\u4e2aRNA\u7247\u6bb5(tile)\uff0c\u5e76\u5229\u7528\u5927\u89c4\u6a21\u5e76\u884c\u5206\u6790\u6cd5\uff0c\u7cfb\u7edf\u6027\u5730\u5206\u6790\u4e86\u8c03\u63a7\u8981\u7d20\u7684\u591a\u6837\u6027\u3001\u8fd0\u4f5c\u673a\u5236\u53ca\u8fdb\u5316\u7279\u5f81\u3002\u7ed3\u679c\u786e\u8ba4\uff0c\u6b64\u524d\u5df2\u77e5\u7684\u5229\u7528TENT4\u9176\u7684\u7b56\u7565\uff0c\u5176\u5b58\u5728\u8303\u56f4\u8fdc\u6bd4\u9884\u60f3\u7684\u66f4\u4e3a\u5e7f\u6cdb\u3002TENT4\u662f\u4e00\u79cd\u7ec6\u80de\u5185\u8c03\u63a7\u9176\uff0c\u53ef\u5728RNA\u672b\u7aef\u5f62\u6210&#8217;\u6df7\u5408\u5c3e\u5df4(mixed 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